Pediatric wheezing associated with respiratory syncytial virus (RSV) and Mycoplasma pneumoniae (MP) infection
Conditions
Interventions
RSV infection group:None
Mycoplasma infection group:None
Sponsors
Shanghai Children’s Hospital
Eligibility
Sex/Gender
All
Age
5 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the Western medical diagnostic criteria for SMPP and the traditional Chinese medicine syndrome differentiation criteria; 2. Children aged 5–14 years; 3. Children or their legal guardians who provide informed consent and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients found by etiological testing within 7 days after admission to have concomitant bacterial, viral, tuberculosis, or other pathogen infections; 2. Patients complicated with asthma or other immune diseases, or those receiving immunomodulatory agents; 3. Patients with severe complications such as heart failure, respiratory failure, or hypoxic encephalopathy; 4. Patients with severe hepatic or renal diseases, cardiovascular diseases, hematological diseases, or neurological diseases, or those with a recent history of severe pneumonia that has not fully resolved; 5. Patients allergic to azithromycin or the investigational traditional Chinese medicine; 6. Patients judged by the physician to be likely to be lost to follow-up; 7. Patients with incomplete medical records.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Healing rate and improvement rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of wheezing;Duration of fever;Duration of cough;White blood cell count;C-reactive protein;Chest imaging;Discharge outcome; | — |
Countries
China
Contacts
Public ContactXiaoping Jing
Shanghai Children’s Hospital
Outcome results
None listed