high-grade squamous intraepithelial lesion
Conditions
Interventions
Observation group:no
Sponsors
Wuhan Fourth Hospital
Eligibility
Sex/Gender
Female
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 45 years; 2. Naturally menopausal for >= 1 year or in the perimenopausal period (irregular menstruation but less than 12 months of amenorrhea); 3. Preoperative cervical biopsy histopathologically confirmed as HSIL (CIN2 or CIN3); 4. Undergoing cervical conization (LEEP or CKC) as initial treatment; 5. Having a complete postoperative pathology report (including margin status).
Exclusion criteria
Exclusion criteria: 1. Previous cervical surgery (conization, LEEP, cryotherapy, laser ablation); 2. Preoperative or postoperative pathology revealing invasive cancer (FIGO >= IA1); 3. Concurrent other gynecologic malignancy; 4. Missing key clinical or pathological data (age, menopausal status, procedure type, pathology outcome).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Margin status;Area Under the Receiver Operating Characteristic Curve (AUC); | — |
Countries
China
Contacts
Public ContactLing Han
Wuhan Fourth Hospital
Outcome results
None listed