Acute Ischemic Stroke
Conditions
Interventions
Clopidogrel Group:Clopidogrel plus Aspirin
Cilostazol Group:Cilostazol plus Aspirin
Sponsors
Drum Tower Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Acute phase of non-cardioembolic ischemic stroke (within 14 days of symptom onset), confirmed by intracranial computed tomography (CT) or magnetic resonance imaging (MRI) on admission; 2. National Institutes of Health Stroke Scale (NIHSS) score =4; 3. Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Missing clinical data; 2. Intracranial arterial stenosis with a degree of >30%; 3. Complicated with hemorrhagic events, such as intracerebral hemorrhage, gastrointestinal bleeding, etc. 4. Use of anticoagulant drugs during hospitalization or follow-up; 5. Interruption of antiplatelet therapy during hospitalization or follow-up; 6. Failure to take cilostazol or clopidogrel for long-term after discharge; 7. Loss to follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrent stroke was confirmed by imaging examinations;Other drug-related adverse reactions;all types of bleeding events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in NIHSS score;New ischemic events, including dizziness, limb weakness, limb numbness, and cardiovascular events;All-cause mortality; | — |
Countries
China
Contacts
Public ContactShao Tengfei
Drum Tower Hospital
Outcome results
None listed