Electroacupuncture for the Prevention of Prolonged Postoperative Ileus After Cytoreductive Surgery for Colorectal Cancer with Peritoneal Metastasis: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600124904

Enrollment

Unknown

Registered

2026-05-19

Start date

2026-06-01

Completion date

Unknown

Last updated

2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prolonged Postoperative Ileus After Cytoreductive Surgery for Colorectal Cancer with Peritoneal Metastasis

Interventions

electroacupuncture group:Standard ERAS + electroacupuncture (bilateral ST36, ST37, SP6), once daily for 20 minutes from postoperative day 1 to day 4, dense-sparse wave (10/50 Hz), current 0.1–1 mA

Conventional ERAS Control Group:Standard ERAS alone (no acupuncture)

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75; 2. Colorectal cancer with peritoneal metastasis confirmed by pathology; 3. Meets the indications for tumor cell reductive surgery; 4. With or without hyperthermic intraperitoneal perfusion therapy.

Exclusion criteria

Exclusion criteria: 1. Severe cardiopulmonary, neurological, or diabetic diseases 2. Prior history of other malignancies 3. Unable to comply with study procedures 4. Coagulation disorders 5. Intolerance or contraindication to acupuncture/electroacupuncture 6. Psychiatric or cognitive impairment 7. History of drug or alcohol abuse 8. Implanted pacemaker or other electronic stimulation device 9. Pregnancy or lactation 10. Preoperative symptoms of ileus 11. Those who need a second operation within 72 hours after the surgery

Design outcomes

Primary

Measure	Time frame
Time to first postoperative bowel movement (hours);	—

Secondary

Measure	Time frame
Time to first flatus;incidence of PPOI;The first time to tolerate a semi-liquid diet after the operation;postoperative pain (VAS);analgesic use ;postoperative complications (Clavien-Dindo classification);I-FEED score;GIQLI score;length of hospital stay;30-day readmission rate;acupuncture-related adverse events;The first time to tolerate a solid diet after surgery;The first time to get out of bed and move around after the operation;The severity of postoperative nausea/vomiting and abdominal distension;The occurrence of other postoperative complications;	—

Measure

Time frame

Time to first flatus;incidence of PPOI;The first time to tolerate a semi-liquid diet after the operation;postoperative pain (VAS);analgesic use ;postoperative complications (Clavien-Dindo classification);I-FEED score;GIQLI score;length of hospital stay;30-day readmission rate;acupuncture-related adverse events;The first time to tolerate a solid diet after surgery;The first time to get out of bed and move around after the operation;The severity of postoperative nausea/vomiting and abdominal distension;The occurrence of other postoperative complications;

—

Countries

China

Contacts

Public ContactWang Yuling

The Sixth Affiliated Hospital of Sun Yat-sen University

wangyl@mail.sysu.edu.cn+86 130 5444 5587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026