Type 2 diabetes, non-proliferative diabetic retinopathy, cataract
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age >= 50-80 years; 2.Experimental group: fasting blood glucose 4.4-12 mmol/L, glycosylated hemoglobin (HbA1c) <= 8%; 3.Lens nuclear hardness of LOCS II-IV grade; 4.Voluntary participation and provision of signed informed consent;
Exclusion criteria
Exclusion criteria: 1.Presence of severe non-proliferative diabetic retinopathy or worse, or diabetic macular edema; 2.High myopia exceeding -6.00 diopters (D), or axial length > 26.5 mm; 3.Presence of other ocular diseases; 4.History of fundus laser therapy, intravitreal injection, or intraocular surgery; 5.Intraoperative serious complications such as posterior capsular rupture or vitreous prolapse; 6.Poor preoperative or postoperative optical coherence tomography angiography (OCTA) image quality or inability to cooperate and complete the examination; 7.Coexistence of severe cardiovascular, respiratory system diseases, or other conditions potentially affecting microcirculation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Macular thickness, , foveal avascular zone (FAZ) area, FAZ perimeter, FAZ acircularity index;Superficial retinal capillary blood flow density in the macular region;Deep retinal capillary blood flow density in the macular area;Deep retinal capillary blood flow density in the macular area; | — |
Countries
China
Contacts
Xiangya Second Hospital of Central South University