FindTrial
Sign In

Sleep spindle wave alterations as a new biomarker for phenotypic stratification in sporadic amyotrophic lateral sclerosis

Exploring REM Sleep Biomarkers in Amyotrophic Lateral Sclerosis and Their Correlation with Disease Onset and Progression Based on Wearable Multi-Physiological Parameter Monitoring and AI Deep Learning Technology

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124897
Enrollment
Unknown
Registered
2026-05-19
Start date
2025-04-01
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amyotrophic Lateral Sclerosis

Interventions

ALS group:None
Healthy control group:None

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ALS Group: Patients aged 18–80 years meeting criteria for clinically confirmed, probable, or possible ALS according to the revised El Escorial criteria; voluntarily participating and having signed an informed consent form. Control Group: Relatives of ALS patients aged 18–80 years; free from severe neurological disorders; having signed an informed consent form.

Exclusion criteria

Exclusion criteria: History of severe traumatic brain injury; severe arrhythmia or heart failure; pacemaker implantation; history of epilepsy; patients refusing to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
Demographic data;Clinical data of ALS disease;Amyotrophic Lateral Sclerosis Functional Rating Scale Score;Sleep Scale Assessment;Evaluation of other non motor symptoms scale;—

Countries

China

Contacts

Public ContactHui Dong

The Second Hospital of Hebei Medical University

huidong@hebmu.edu.cn+86 180 3213 5515

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026