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Comparison of SOFA-1 and SOFA-2 Scores for Predicting Mortality in Patients Undergoing Cardiac Surgery: A Multicenter Retrospective Cohort Study Protocol

Comparison of SOFA-1 and SOFA-2 Scores for Predicting Mortality in Patients Undergoing Cardiac Surgery: A Multicenter Retrospective Cohort Study Protocol

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124888
Enrollment
Unknown
Registered
2026-05-19
Start date
2026-05-19
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative mortality after cardiac surgery

Interventions

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >=18 years; 2. Underwent cardiac surgery with cardiopulmonary bypass at one of the four participating cardiac centers; 3. Had at least one postoperative record of all variables required to calculate the SOFA score; 4. Had complete clinical data allowing calculation of both SOFA-1 and SOFA-2 scores.

Exclusion criteria

Exclusion criteria: 1. Died within 24 hours after surgery; 2. Did not complete at least one postoperative SOFA score assessment due to missing key variables required for SOFA score calculation, such as GCS, vasoactive drug dose, platelet count, creatinine, bilirubin, PaO2/FiO2, etc.; 3. Had pre-existing severe organ dysfunction before surgery, such as end-stage liver disease, end-stage renal disease, long-term mechanical ventilation, etc.; 4. Had duplicate baseline assessment data or logical errors affecting baseline assessment.

Design outcomes

Primary

MeasureTime frame
All-cause mortality during hospitalization;

Secondary

MeasureTime frame
ICU length of stay;Postoperative mechanical ventilation duration;

Countries

China

Contacts

Public ContactLin Jing

West China Hospital of Sichuan University

350576038@qq.com+86 28 85423593

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026