Propofol injection pain
Conditions
Interventions
Children aged 5 to 7 years:Intravenous lidocaine pretreatment was followed 15 seconds later by a fixed dose of propofol (2.5 mg/kg)
Children aged 2 to 4 years:Intravenous lidocaine pretreatment was followed 15 seconds later by a fixed dose of propofol (2.5 mg/kg)
Sponsors
Foshan Women and Children Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 7 Years
Inclusion criteria
Inclusion criteria: 1.Pediatric patients scheduled for general anesthesia at Foshan Women and Children Hospital were selected. 2.Age 2 to 7 years old, gender not limited; 3.American Society of Anesthesiologists (ASA) classification grades ? to ?; 4.Patients with Mallampati class I or II and normal development; 5.A 24-gauge intravenous cannula was placed in the dorsum of the hand. 6.The family members sign the informed consent form for the clinical trial.
Exclusion criteria
Exclusion criteria: 1.A history of allergy or contraindication to any of the study medications. 2.Patients were excluded if they had an acute upper respiratory tract infection; 3.Difficult airway; 4.Use of sedatives (such as midazolam or barbiturates), psychotropic agents, or opioids within 7 days prior to surgery. 5.A newly inserted peripheral intravenous cannula; 6.Patients were excluded if they exhibited either excessive crying/agitation that compromised anesthesia assessment or a psychiatric disorder precluding cooperation. 7.Presence of asthma, congenital heart disease, arrhythmia, or severe hematological, renal, or hepatic disease. 8.Those whom the investigator deems unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite pain score for propofol injection pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse Event;NIBP?HR?SpO2;MOAA/S score; | — |
Countries
China
Contacts
Public ContactChen Yifei
Foshan Women and Children Hospital
Outcome results
None listed