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High-Flow Nasal Cannula versus Nasopharyngeal Airway for Prevention of Hypoxemic Events in Elderly Patients Undergoing Painless Bronchoscopy: A Randomized Controlled Trial

High-Flow Nasal Cannula versus Nasopharyngeal Airway for Prevention of Hypoxemic Events in Elderly Patients Undergoing Painless Bronchoscopy: A Randomized Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600124873
Enrollment
Unknown
Registered
2026-05-18
Start date
2025-12-17
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative Hypoxemia

Interventions

Control group:Nasopharyngeal airway with routine oxygen administration
Experimental group:High-flow oxygen therapy

Sponsors

Lishui Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) physical status classification II-III; 2. Age 60-80 years; 3.Body Mass Index (BMI) 18-28 kg/m^2; 4.Patients undergoing painless bronchoscopy; 5.Voluntary participation in the trial with signed informed consent.

Exclusion criteria

Exclusion criteria: 1.Complicated with severe cardiac, hepatic, or renal diseases; 2.Difficult airway management due to severe facial deformity, temporomandibular joint ankylosis, ankylosing spondylitis, etc.; 3.Nasal polyps, nasal bleeding or bleeding tendency, nasal trauma, nasal deformity, obvious nasal septum deviation, or previous nasal surgery (septoplasty, turbinectomy); 4.Abnormal coagulation mechanism, skull base fracture, cerebrospinal fluid otorrhea or rhinorrhea; 5.Vomiting, regurgitation, aspiration, or high risk thereof, such as non-fasting, full stomach, intestinal obstruction, hiatal hernia; 6.Severe allergy history or psychiatric disorders preventing cooperation with anesthesia; 7.Lack of autonomous consciousness or decision-making capacity; 8.Currently enrolled in other interventional clinical trials.

Design outcomes

Primary

MeasureTime frame
Hypoxic event;

Secondary

MeasureTime frame
Arterial blood gas at patient admission and at the end of the procedure;The occurrence of adverse events within 24 hours after surgery, such as nausea, vomiting, dizziness, nosebleeds, etc.;The total dose of sedative drugs;The incidence of adverse events such as hypercapnia, reflux aspiration, epistaxis, and the number of interruptions during examination.;After the surgery, investigate the satisfaction of the patient and the endoscopist;Check-in time, awakening time, stay time in the recovery room;

Countries

China

Contacts

Public ContactChuanguang Wang

Lishui Central Hospital

wcg0033@wmu.edu.cn+86 578 2285668

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026