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Gut Microbiome and Metabolomic Signatures, Diagnostic Prediction Modeling, and Mechanistic Insights in Stricturing Crohn's Disease

Gut Microbiome and Metabolomic Signatures, Diagnostic Prediction Modeling, and Mechanistic Insights in Stricturing Crohn's Disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124871
Enrollment
Unknown
Registered
2026-05-18
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn's Disease

Interventions

Control group:None
Non-stricturing Crohn's disease group:none
Stricturing Crohn's disease group:None

Sponsors

The First A?liated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Diagnosed with Crohn's disease; 2. Diagnosed with CD through endoscopy or imaging, with or without intestinal lumen stricture; 3. No history of antibiotic or probiotic use in the past three months.

Exclusion criteria

Exclusion criteria: Pregnancy, autoimmune diseases, hematologic disorders, malignant tumors, chronic liver and kidney diseases, as well as severe cardiovascular, cerebrovascular, and pulmonary diseases.

Design outcomes

Primary

MeasureTime frame
Fecal microbiota;Fecal untargeted metabolomics features;Serum untargeted metabolomics features;Mucosal microbiota;—

Countries

China

Contacts

Public ContactHongjie Zhang

The First A?liated Hospital of Nanjing Medical University

hjzhang06@163.com+86 139 5197 5918

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026