acute ischemic stroke
Conditions
Sponsors
The Second Affiliated Hospital of the Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age = 18 years with no upper age limit. 2.Clinically diagnosed or imaging-confirmed acute ischemic stroke. 3.Acute occlusion of a large or major intracranial artery confirmed by DSA, CTA, or MRA. 4.ritten informed consent obtained from the patient or their legally authorized representative/guardian.
Exclusion criteria
Exclusion criteria: 1.Intracranial hemorrhage confirmed by head CT or MRI. 2.Pregnant or breastfeeding women. 3.Pre-existing non-stroke conditions with expected survival <6 months (e.g., advanced cancer, end-stage renal disease, Alzheimer's disease, severe infectious disease, amyotrophic lateral sclerosis). 4.Expectation of inability to complete follow-up. 5.Intracranial space-occupying lesion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptomatic intracranial hemorrhage (SICH) within 48 hours;90 days favorable outcomes (%);Proportion of patients with 90-day mRS 0-3; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of patients with 10-year mRS 0-3;Distiburion of 5-year mRS Score;Proportion of patients with 5-year mRS 0-3;Distiburion of 5-year mRS Score;Incidence of non-intracranial bleeding complications;Proportion of patients with 1-year mRS 0-2;90-day EQ-5D utility index score;Change in NIHSS score at 5-7 days post-treatment (If the time of discharge is earlier than 5-7 days, it is the time of discharge);Proportion of patients with 3-year mRS 0-3;Proportion of patients with 20-year mRS 0-2;Proportion of patients with 20-year mRS 0-3;Distiburion of 20-year mRS Score;Asymptomatic intracranial hemorrhage within 48 hours;Proportion of patients with 90-day mRS 0-4;Distiburion of 90-day mRS Score;Proportion of patients with 15-year mRS 0-3;Proportion of patients with 15-year mRS 0-2;Distiburion of 1-year mRS Score;All-cause mortality at 90 days;Distiburion of 3-year mRS Score;Proportion of patients with 3-year mRS 0-2;Proportion of patients with 5-year mRS 0-2;Proportion of patients with 10-year mRS 0-2;Proportion of patients with 1-year mRS 0-3;Distiburion of 15-year mRS Score; | — |
Countries
China
Contacts
Public ContactWenjie Zi
The Second Affiliated Hospital of the Army Medical University
Outcome results
None listed