None
Conditions
Interventions
Test Group:Lysine Calcium Magnesium Zinc Liquid Drink (Witsbb Grow Pro+ TalPlax Drink 2)
Placebo Group:Placebo
Sponsors
Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health
Eligibility
Sex/Gender
All
Age
8 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1. Children aged 8-14 years old, regardless of sex; 2. height-for-age Z score less than -1, those who have just entered puberty; 3. fully understand the nature, purpose, benefits, and potential risks and side effects of this study, and can objectively cooperate with physicians to complete the examination and evaluation of disease and physical condition; 4. those who voluntarily agree and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who have used or are using growth hormone, whose epiphyseal plates have closed, with abnormal thyroid function, type 1 diabetes, tumors, abnormal liver and kidney function; 2. those with diseases that severely affect the digestion and absorption of the trial supplies; 3. subjects with symptomatic and difficult-to-control neurological, psychiatric diseases or mental disorders; 4. those allergic to the components of the test food; 5. those taking supplemental foods and health supplements with the same efficacy within 4 weeks before the trial and during the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood routine indicators;Blood biochemistry indicators;Urinalysis indicators;25-hydroxy vitamin D panel;Blood minerals: 9 trace elements (including lead and cadmium);Thyroid function: five thyroid function items;Blood osteocalcin (OST), bone alkaline phosphatase;Blood insulin-like growth factor-1;Sex hormones: six sex hormone items + SHBG LH FSH E2 T PRL PGN;gm4 quantitative food allergen;Bone density: lumbar spine bone density, left hip joint bone density, right hip joint bone density;Abdominal ultrasound D (liver, gallbladder, pancreas, spleen + lymph nodes);Human metabolic dynamics measurement analysis;Dietary assessment and dietary guidance; | — |
Countries
China
Contacts
Public ContactHongmei Huang
Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health
Outcome results
None listed