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A 7-Day Randomized Controlled Trial and Follow-Up Cohort Study on Lipid-Metabolic Balance Nutrition Modulating Immune Homeostasis and Lowering Uric Acid

A 7-Day Randomized Controlled Trial and Follow-Up Cohort Study on Lipid-Metabolic Balance Nutrition Modulating Immune Homeostasis and Lowering Uric Acid

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600124826
Enrollment
Unknown
Registered
2026-05-18
Start date
2026-05-19
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperuricemia

Interventions

Precision Nutrition Intervention Group:Without interfering with normal clinical diagnosis and treatment, based on the results of the subject's blood fatty acid profile, personalized supplementation wi
Control Group:Under the premise of not affecting normal clinical diagnosis and treatment, there are no other interventions except providing standard low-purine diet guidance. During the study period,

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.The selected patients should meet the following conditions: (1)Age 18–65 years; (2)Diagnosed with hyperuricemia (male serum UA >420 µmol/L, female serum UA >360 µmol/L) by a secondary or tertiary hospital, and hs-CRP >2.0 mg/L; (3)Subjects voluntarily participate in the study and sign the informed consent form; (4)Subjects can understand the content of the questionnaire and complete it independently or with the help of the investigator.

Exclusion criteria

Exclusion criteria: If the subjects have any of the following circumstances, they should be excluded from the study: (1) Renal insufficiency, active gout, severe systemic diseases, pregnant or lactating women; (2) Tendency toward violence, aggressiveness, or being a danger to themselves or others; (3) Subjects who give up midway while filling out the questionnaire and stop completing it; (4) Subjects who are unable to communicate normally with the investigator; (5) Patients who, in the opinion of the investigator, are unsuitable to participate in the study for other reasons.

Design outcomes

Primary

MeasureTime frame
Blood fatty acid profile;The influence of precision nutritional intervention on the blood uric acid level of patients with hyperuricemia;

Secondary

MeasureTime frame
General information of patients;Patient's clinical data (blood uric acid, liver and kidney function, blood lipids, blood routine, insulin, blood glucose, hs-CRP, IL-6, sCD40L, etc.);Patient's clinical data (blood uric acid, liver and kidney function, blood lipids, blood routine, insulin, blood glucose, hs-CRP, IL-6, sCD40L, etc.);Investigate the distribution of various fatty acid proportions in the blood of patients with hyperuricemia in our country;Exploring the association between Hashimoto's hyperuricemia and fat metabolism;

Countries

China

Contacts

Public ContactLiu Yinghua

Chinese PLA General Hospital

liuyinghua77@163.com+86 10 6693 7785

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026