Infertility
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients who meet all the inclusion criteria below can be included in this study: 1. Age >= 22 and < 40 years old; 2. Clinically diagnosed with infertility, with at least one indication for IVF/ICSI, and planned to receive an antagonist fixed protocol treatment based on goserelin acetate; 3. Have signed the informed consent form.
Exclusion criteria
Exclusion criteria: Any of the following conditions disqualifies an individual from being included in the study: 1. Patients with contraindications for assisted reproductive technology or pregnancy restrictions; 2. Any chromosomal abnormalities in either parent; 3. History of recurrent miscarriage; 4. Abnormalities in the uterus or fallopian tubes: presence of uterine abnormalities (unresolved endometrial fibroids, intrauterine adhesions, uterine malformations, etc.) or fallopian tube abnormalities (such as untreated tubal hydrosalpinx); 5. Ovarian pathology: existing ovarian pathological conditions; 6. Severe male infertility caused by male factors: including but not limited to: severe oligoasthenospermia (such as sperm concentration < 5×10^6/mL, or forward motile sperm percentage < 10%, or normal morphology rate < 1%); azoospermia (non-obstructive); the male is known to carry genetic diseases or chromosomal structural abnormalities (unless PGT-SR/PGT-M has been performed); 7. The male's semen sample cannot be obtained or the individual refuses to provide it (such as due to surgery, illness, or other reasons); 8. Missing core data collected retrospectively (LH test values).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Live birth rate per initiated cycle; | — |
Secondary
| Measure | Time frame |
|---|---|
| Day 3 and Day 5 embryo quality;Number of oocytes retrieved;Embryo implantation rate;Biochemical pregnancy rate;Clinical pregnancy rate;Cumulative live birth rate;Cycle cancellation rate; | — |
Countries
China
Contacts
Lishui People's Hospital