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Hidden Fatigue Unmasked by Music: A Novel FSS × RMSSD Dual-Dimensional Framework Detects Covert Autonomic Insufficiency in Night-Shift Nurses Following Standardised Music Therapy

Hidden Fatigue Unmasked by Music: A Novel FSS × RMSSD Dual-Dimensional Framework Detects Covert Autonomic Insufficiency in Night-Shift Nurses Following Standardised Music Therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600124796
Enrollment
Unknown
Registered
2026-05-18
Start date
2026-05-20
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Night shift-related fatigue with subjective-objective dissociation

Interventions

Test group:Passive Receptive Music Therapy

Sponsors

Affiliated Chenggong Hospital of Xiamen University (73rd Army Group Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Registered medical staff (including nurses, resident physicians, and other clinical personnel participating in night shifts) engaged in clinical work at the study hospital. 2. Aged 18 to 55 years. 3. At least 6 months of work experience, with a documented history of regular night shift scheduling within the past 3 months (average of =4 night shifts per month). 4. Completed a standard night shift (=8 hours) prior to the study day, and in a post-night shift state on the day of enrollment. 5. Normal hearing ability (able to perceive speech and music normally without the need for a hearing aid). 6. Willing to participate and provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. Diagnosed with arrhythmia, atrial fibrillation, or have a pacemaker implanted (may affect HRV validity). 2. Currently taking medications that affect heart rate (e.g., beta-blockers, antiarrhythmic drugs, atropine, etc.). 3. Diagnosed with moderate or severe sleep apnea syndrome. 4. Consumption of alcohol or use of sedative/hypnotic medications within 24 hours prior to the study. 5. Diagnosed with depression, anxiety disorder (currently undergoing active treatment), or other psychiatric conditions. 6. Experienced major life stress events (e.g., death of a relative, divorce, etc.) within the past 3 months. 7. Pregnant or breastfeeding women. 8. Currently participating in another interventional clinical study.

Design outcomes

Primary

MeasureTime frame
Fatigue Severity Scale (FSS);Objective Autonomic State (PPG-RMSSD); Fatigue Phenotype Quadrants (FSS × RMSSD Two dimensional Quadrant Classification Model: Quadrant A/B/C/D);

Secondary

MeasureTime frame
State?Trait Anxiety Inventory (STAI-State, 20 items);Pittsburgh Sleep Quality Index (PSQI, 19 items);Stress related hormone indicators;Cumulative night shift exposure;

Countries

China

Contacts

Public ContactPengxia Wang

Department of Anesthesia, Affiliated Chenggong Hospital of Xiamen University

1843149196@qq.com+86 188 3418 5856

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026