Patients who are scheduled to undergo open reduction and internal fixation for ankle fractures
Conditions
Interventions
Control group:The control group received a nerve block injection of 0.375% ropivacaine and 5mg dexamethasone, totaling 30ml.
Trial group:The experimental group injected 133mg of bupivacaine lipid emulsion in 20ml of physiological saline, totaling 30ml.
Sponsors
Wuxi 9th Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.If the surgical indications are met, ankle surgery will be performed at an elective date. 2. Age 18 to 60 years old; 3. Classified as grade I to II by the American Society of Anesthesiologists (ASA); 4. Be able to correctly understand and answer questions, and accurately express the feeling of pain.
Exclusion criteria
Exclusion criteria: 1. Related allergies; 2. Current gastrointestinal bleeding; 3. Other injuries requiring opioid analgesics; 4. Habitual daily use of opioids; 5. Cognitive or mental function disorders or substance abuse; 6. Logistical reasons; 7. Lower limb neurological dysfunction; 8. Pregnancy or breastfeeding; 9. Injection site infection; 10. Acute porphyria; 11. Kidney disease requiring dialysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of rebound pain;Rebound pain occurs when and lasts; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS pain score;Opioid consumption;Postoperative nausea and vomiting;Sleep quality score;Quality of recovery scores; | — |
Countries
China
Contacts
Public ContactWang Meng
Wuxi 9th Affiliated Hospital of Soochow University
Outcome results
None listed