Traumatic hemorrhagic Shock
Conditions
Interventions
General type O red blood cells / Non-general type O red blood cells observation group:None
Sponsors
Jinling Hosptial affiliated to Nanjing University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 18 - 70 years old; 2. New trauma within 6 hours; 3. Trauma combined with hemorrhagic shock, and the blood consumption score (ABC score) >= 2 points (including 4 indicators: penetrating injury; positive result of trauma ultrasound focused assessment (FAST); systolic blood pressure = 120 beats per minute; each parameter is counted as 1 point); 4. The patient or the authorized representative has signed the informed consent form; 5. The subjects can follow the treatment plan of this study.
Exclusion criteria
Exclusion criteria: 1.Pregnant and lactating women; 2. Patients who have received component blood transfusion within the past three months; 3. Patients with known RhD negativity and a history of anti-D antibody positivity; 4.Patients with severe underlying diseases (e.g., advanced liver cirrhosis, end-stage renal disease, congestive heart failure NYHA class IV, advanced malignancy); 5.Non-traumatic patients, including those with hematological disorders or other indications for component blood transfusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total blood transfusion volume within 24 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Transfusion reactions: including the incidence of adverse transfusion reactions such as hemolytic reactions and acute renal insufficiency;Blood transfusion time;The total volume of resuscitation fluid within 24 hours;24-hour and 30-day mortality rates; ICU length of stay; | — |
Countries
China
Contacts
Public ContactDing Weiwei
Jinling Hospital affiliated to Nanjing University
Outcome results
None listed