Congenital Diaphragmatic Hernia
Conditions
Interventions
CDH group:None
Control group (normal fetus group):None
Sponsors
Chongqing Health Center for Women and Children
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for the experimental group: (1) singleton pregnancy; (2) Confirmed as CDH by prenatal ultrasound or MRI; (3) Have complete fetal MRI examination data; 2. Inclusion criteria for the control group: (1) singleton pregnancy; (2) Gestational age: 260,000-370,000 weeks; (3) Prenatal MRI examination showed no abnormal lung development imaging manifestations. (4) The postpartum Apgar score is normal; (5) There were no abnormal clinical manifestations of the respiratory system after birth.
Exclusion criteria
Exclusion criteria: 1. Exclusion criteria for the study group (CDH group): (1) Presence of other major congenital structural anomalies; (2) Incomplete clinical or imaging data; (3) Pregnancy termination or miscarriage, or withdrawal of treatment after birth. 2. Exclusion criteria for the control group: (1) Any fetal structural anomaly or suspected anomaly; (2) Significant maternal comorbidities during pregnancy (e.g., gestational diabetes mellitus, gestational hypertension); (3) Severe respiratory problems requiring intervention in the early postnatal period; (4) Missing data or suboptimal MRI image quality.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Discharge survival status (alive/dead); | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary hypertension;Duration of mechanical ventilation (days);Length of hospital stay (days);Need for respiratory support at discharge (yes/no); | — |
Countries
China
Contacts
Public ContactYang Qiaoli
Chongqing Health Center for Women and Children
Outcome results
None listed