Preoperative anxiety
Conditions
Interventions
A group (control group):Normal saline (1 ml sterile normal saline)
B group (experimental group):1.0<=dose<1.5 µg/kg dexmedetomidine nasal spray
C group (experimental group):1.5<=dose<2.0 µg/kg dexmedetomidine nasal spray
D group (experimental group):2.0<=dose<2.5 µg/kg dexmedetomidine nasal spray
Sponsors
Zhuhai People's Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1.The legal guardian(s) of the child provided written informed consent to participate in this study. 2.Pediatric patients scheduled to undergo adenoidectomy under general anesthesia. 3.The child patient is 2 to 6 years old, with ASA grade I to II.
Exclusion criteria
Exclusion criteria: 1.Patients with severe cardiopulmonary diseases or hepatic/renal dysfunction/failure; 2.Patients with a Body Mass Index (BMI) greater than 30; 3.Patients with a recent history of upper respiratory tract infection or asthma; 4.Patients with severe malnutrition; 5.Patients with a documented history of allergy to the study drug; or those who have used a2 receptor agonists or antagonists, or other medications that may interfere with the study results, within the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Yale Preoperative Anxiety Scale Score;Pediatric Postoperative Pain Score;Pediatric Emergence Delirium Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood Pressure, Heart Rate, and Oxygen Saturation;Bispectral Index (BIS) Value;Emergence Time; | — |
Countries
China
Contacts
Public ContactLi Guangtian
Zhuhai People's Hospital
Outcome results
None listed