hip surgery
Conditions
Interventions
Remimazolam group(RZ):"During anesthetic induction, remimazolam was administered intravenously at a dose of 0.2–0.3 mg/kg. A sham coil (D70 Air Film Coil, Magstim) was placed over the left DLPFC while
Transcranial Magnetic Stimulation group(TMS):"Upon tracheal extubation in the PACU, transcranial magnetic stimulation (TMS) was applied to the patients. High-frequency TMS (10 Hz) was delivered to the
Transcranial magnetic stimulation plus remimazolam group (TMS + RZ group):"During anesthetic induction, remimazolam was administered intravenously at a dose of 0.2–0.3 mg/kg. Immediately after trachea
Sponsors
The First Affiliated Hospital of Bengbu Medical College
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Undergoing elective hip surgery; 2.No gender restriction, aged 60 years or older; 3.Written informed consent obtained from the patients and their families; 4.Assessed as able to tolerate general anesthesia.
Exclusion criteria
Exclusion criteria: 1.Refusal to sign informed consent; 2.Pre-existing mental disorders, psychological disorders, neurocognitive disorders, or a history of central nervous system diseases; 3.Visual or hearing impairment, or communication difficulties; 4.Skull or scalp injury; 5.Drug or alcohol abuse; 6.Presence of metallic implants, cardiac pacemaker, or cochlear implant; 7.Severe cardiovascular or cerebrovascular disease; 8.Mini-Mental State Examination (MMSE) score (range: 0–30, with lower scores indicating worse cognitive function) below 15; 9.Allergy to remimazolam; 10.Other conditions deemed unsuitable for participation by the investigator or attending physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15 (QoR-15) on postoperative days 1, 2, and 3; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score;Incidence of POD;Postoperative complications; | — |
Countries
China
Contacts
Public ContactCongli Zhang
The First Affiliated Hospital of Bengbu Medical College
Outcome results
None listed