Hepatocellular Carcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18–75 years; 2. Recurrence after radical resection for primary hepatocellular carcinoma (HCC), underwent repeat hepatectomy with a pathological confirmation of HCC; 3. Medical records available to allow preoperative assessment of MVI risk using a nomogram model; 4. The width of the surgical margin was clearly documented in the pathological report; 5. Complete medical records were available (including baseline characteristics, operative records, and follow-up data).
Exclusion criteria
Exclusion criteria: 1. The first hepatectomy was non-radical resection. 2. Tumor recurrence was diagnosed within 1 year after primary surgery. 3. Recurrent tumors were multiple, with a diameter > 5 cm, or located adjacent to vital anatomical structures, resulting in surgical difficulty. 4. Extrahepatic metastasis and tumor thrombus in the main portal vein, hepatic vein, or bile duct were present in both primary and recurrent tumors. 5. Liver function was worse than Child-Pugh Class A before repeat hepatectomy. 6. Received systemic anti-tumor therapy prior to re-hepatectomy (e.g., TACE or other interventional therapy, targeted therapy, immunotherapy). 7. Complicated with other malignant tumors. 8. Missing key information in medical records (e.g., surgical margin width, MVI risk score, follow-up data).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Over Survival;Recurrence rate; | — |
Countries
China
Contacts
Department of Hepatobiliary and Pancreatic Surgery, the Tenth People’s Hospital of Tongji University