Limbal stem cell deficiency
Conditions
Interventions
Healthy control group:None
Mild to moderate limbal stem cell deficiency group:None
Severe limbal stem cell deficiency group:None
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18 years or older, under 65 years old. Gender: No restrictions. Both eyes or single eye affected: No restrictions. 2.After fully understanding the content of this study, the patient voluntarily participated and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Those whose enrolled eyes had a history of previous ocular surgeries; 2.Severe underlying systemic diseases; 3.Patients with infectious diseases; 4.Patients with severe genetic diseases; 5.Women during pregnancy or lactation period;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Multimodal AI model diagnostic performance; | — |
Secondary
| Measure | Time frame |
|---|---|
| AS-OCT corneal structural parameters;Key protein biomarker;Quantitative indicators of corneal fluorescein staining; | — |
Countries
China
Contacts
Public ContactLiangbo Chen
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed