Early gastric cancer
Conditions
Interventions
Early-stage gastric cancer observation group:None
Sponsors
Affiliated Hospital of Jiangsu University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18 - 65 years old; 2. Preoperative diagnosis of early gastric cancer confirmed by gastroscopy biopsy pathology; 3. Through MDT collaboration assessment: The pathology department determined the tumor differentiation through immunohistochemistry, the endoscopy department determined the tumor stage and invasion depth through endoscopic ultrasound, and the gastro surgery department, digestive internal medicine department, and anesthesia department jointly evaluated whether it met the indications of LECS + ICG-SNNS; 4. No anti-tumor treatment such as chemotherapy or radiotherapy was received before the surgery; 5. The patient and his/her family gave informed consent and signed the consent form; 6. There were no contraindications for surgery, anesthesia, or ICG use, and the physical condition was tolerable for the surgery; 7. The patient and his/her family could cooperate to complete the 12-month postoperative follow-up and related re-examination items.
Exclusion criteria
Exclusion criteria: 1. Those who do not meet the indications of LECS+ICG-SNNS after MDT collaborative assessment; 2. Age less than 18 years or more than 65 years; 3. Complicated with severe underlying diseases: cardiac function > grade II (NYHA), severe hypertension (systolic blood pressure >= 180 mmHg or diastolic blood pressure >= 110 mmHg), severe liver and kidney dysfunction (Child-Pugh >= 10 points, creatinine clearance rate < 25 ml/min), respiratory insufficiency, coagulation dysfunction; 4. Allergic to indocyanine green (ICG), anesthetics, cephalosporin antibiotics and other commonly used perioperative drugs; 5. Complicated with complete gastrointestinal obstruction, emergency surgery or palliative surgery; 6. Surgery requires combined resection of other organs such as spleen and pancreas; 7. Malnutrition or severe malnutrition (albumin <= 0 g/L, BMI < 18); 8. Pregnant, lactating women or those with pregnancy plans within 1 month after the trial (including male participants); 9. Those who have participated in other clinical trials in the past 3 months; 10. The sponsors, investigators or their family members directly involved in the trial; 11. Pathologically confirmed as advanced gastric cancer or other types of tumors (squamous cell carcinoma, neuroendocrine tumor, gastrointestinal stromal tumor, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MDT assessment consistency rate;Tumor resection rate;Detection rate of sentinel lymph nodes; | — |
Secondary
| Measure | Time frame |
|---|---|
| First bowel movement time;PG-SGA Nutritional Score; | — |
Countries
China
Contacts
Public ContactXin Fan
Affiliated Hospital of Jiangsu University
Outcome results
None listed