Effect of transcutaneous auricular vagus nerve stimulation on the quality of early recovery in patients undergoing laparoscopic kidney surgery under general anesthesia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600124726

Enrollment

Unknown

Registered

2026-05-15

Start date

2026-05-15

Completion date

Unknown

Last updated

2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary renal disease requiring surgical management

Interventions

a-taVNS Group (Real stimulation):Transcutaneous auricular vagus nerve stimulation (taVNS): frequency 20 Hz, pulse width 200 µs, intensity slightly below subjective perception level

stimulation site: cymba concha

treatment timing: afternoon of the day before surgery, after extubation in post-anesthesia recovery room, afternoon of postoperative day 1, and afternoon of postoperative day 2, total 4 sessions, each

s-taVNS group (pseudostimulation/control group):Sham transcutaneous auricular vagus nerve stimulation (taVNS): device set to 0 mA output (no electrical stimulation), but retaining operational indicato

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age 18 years and older; 2. BMI 18.5~30 kg/m^2; 3. ASA grade I.~II.; 4. Laparoscopic renal surgery under general anesthesia; 5. actively cooperate; Complete clinical data.

Exclusion criteria

Exclusion criteria: 1. Refusal to sign the trial consent form; 2. Those with severe neurological dysfunction, cognitive dysfunction and mental illness; Mini-Mental Scale score < 15 points; 3. Long-term use of cortisol drugs or antidepressant, anxiety, sleep disorders and other psychotropic drugs and analgesics; 4. Implantation of electronic devices (e.g., pacemakers, vagus nerve stimulators, etc.); 5. Preoperative heart rate < 50 beats/min or presence of sinus node lesions, second-degree or above atrioventricular block; 6. Otodermatitis or conch injury.

Design outcomes

Primary

Measure	Time frame
15-item quality of recovery rating scale (QoR-15) at 24 hours after surgery;	—

Secondary

Measure	Time frame
Drainage tube indwelling time;15-item recovery quality rating scale (QoR-15) at 48 hours after surgery;Time to first flatus;VAS score at 24 and 48 hours after surgery;Incidence of nausea and vomiting;	—

Countries

China

Contacts

Public ContactZhu Lijiao

Xuzhou Central Hospital

941700151@qq.com+86 516 83956181

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026