Laparoscopic surgery
Conditions
Interventions
Control group:Transcutaneous vagus nerve pseudo stimulation
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Elective abdominal surgery under general anesthesia (including laparoscopic cholecystectomy, appendectomy, hernia surgery, etc.), with an estimated operation duration of 1 to 3 hours; 2.Age: 18 to 65 years old; 3.ASA physical status: Class ? to ?; 4.BMI: 18.5 to 28 kg/m^2; 5.Clear consciousness and normal communication capability; 6.Voluntary participation in this study with signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with damaged, infected or deformed ear skin, unable to place electrodes; 2. Patients with known vagus nerve dysfunction or a history of neck surgery; 3. Patients with severe cardiovascular diseases (NYHA grades ?-?, severe arrhythmia, implanted pacemaker/ICD); 4. Patients with neurological diseases (epilepsy, Parkinson's disease, history of stroke); 5. Patients who have been using analgesics, sedatives or antidepressants for a long time; 6. Patients with hearing impairment or those who cannot understand the research process; 7. Pregnant or lactating women; 8. Patients participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The dosage of propofol during the induction period of anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| The cumulative dosage of analgesic drugs within 24 hours after the operation;The dosage of propofol and remifentanil during the maintenance period of anesthesia;Anesthesia depth monitoring indicators;Hemodynamic indicators;Quality indicators of awakening;NRS scores at each postoperative time point;Postoperative adverse events; | — |
Countries
China
Contacts
Public ContactLi Xianglong
Guangdong Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed