pulmonary fibrosis
Conditions
Interventions
Observation group:None
Sponsors
Army Medical Center of PLA
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age between 18 and 80 years; 2.Definite diagnosis of pulmonary fibrosis based on clinical evaluation, HRCT, and/or histopathology (IPF diagnosed according to ATS/ERS/JRS/ALAT criteria: typical or probable UIP pattern on HRCT); 3.Signed informed consent and willingness to participate in long-term follow-up.
Exclusion criteria
Exclusion criteria: 1.Comorbid severe systemic diseases or organ failure (including but not limited to cardiac, hepatic, or renal failure); 2.Active malignant tumors or severe mental illness; 3.Acute interstitial lung changes secondary to active pulmonary infection (e.g., tuberculosis, fungal infection); established post-infectious fibrosis is not an exclusion; 4.Unavailable baseline HRCT (inability to obtain HRCT at enrollment without possibility of later acquisition); 5.Terminal illness with expected survival <6 months attributable to causes other than pulmonary fibrosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-Cause Mortality;Disease Progression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung Transplantation;First Hospitalization Due to Respiratory Disease;Acute Exacerbation;Progression-Free Survival; | — |
Countries
China
Contacts
Public ContactLi Li
Army Medical Center of PLA
Outcome results
None listed