Epilepsy
Conditions
Interventions
Observationl group:None
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
14 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age = 14 years. 2.Need Intracranial electrodes implantation for clinical reasons, with planned elective surgery for electrode implantation and/or removal. 3.Adequate basic auditory and/or visual function to receive study-related auditory or visual stimuli (used for anesthesia induction and related paradigms). 4.Ability to understand the study protocol while awake and to provide voluntary written informed consent. 5.For subjects <18 years old, informed consent signed by a legal guardian, with the subject's own assent obtained. 6.Preoperative anesthesia evaluation confirms tolerability of the intended anesthesia/sedation procedure.
Exclusion criteria
Exclusion criteria: 1.Presence of severe dysfunction of vital organs such as the heart, lungs, liver, or kidneys, or assessment by the anesthesiologist indicating that the subject is unsuitable for participating in study-related recordings. 2.Past or current presence of severe psychiatric disorders, severe cognitive impairment, or other conditions that impede the ability to understand or comply with the study procedures. 3.Presence of significant auditory or visual impairments that preclude the ability to complete study-related stimulus presentation. 4.Preoperative evaluation suggesting a high perioperative risk, leading the investigator to deem the subject unsuitable for inclusion. 5.Any other conditions deemed by the investigator to make the subject unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in inter-regional functional connectivity strength before and after loss of responsiveness;Changes in EEG Time-Frequency Features; | — |
Countries
China
Contacts
Public ContactRuijing Wang
Huashan Hospital, Fudan University
Outcome results
None listed