Patients with upper limb hand dysfunction after stroke
Conditions
Interventions
Kinesthetic motor imagery group:BCI training based on kinesthetic motor imaging during the intervention
Mixed Movement Imagination Group:Brain-computer interface training based on hybrid motor imagery
Visuomotor imagination group:BCI training based on vision motor imaging during the intervention
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
25 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. It meets the diagnostic criteria for cerebral infarction and cerebral hemorrhage in the "Key Points for the Diagnosis of Various Major Cerebrovascular Diseases in China 2019". 2. The course of the disease is 7 days ~ 6 months, and the matter is undergoing rehabilitation training; 3. The age is 25~80 years old, and there is no gender limit; 4. Patients with upper limb motor function classified as Brunnstrom stage ? to ? 5. Vital signs are stable and able to complete routine post-stroke rehabilitation assessments; 6. Have certain motor imagination ability: Kinesthetic and Visual Imagination Questionnaire (KVIQ-20) >=55 points; 7. Those who have no cognitive impairment (MMSE >= 20 points) and can sign the informed consent form to voluntarily participate in this study.
Exclusion criteria
Exclusion criteria: 1. Presence of any disease or symptom (second stroke, fall, fracture) that may be aggravated or result in adverse effects by exercise; 2. Use of drugs that affect muscle tone within 1 month; 3. Those whose fractures have not healed or undergone internal fixation or bone and joint tumors; 4. Those who have broken skin surfaces on the scalp and upper limbs or have metal implants in the skull; 5. Personal history of epilepsy or seizures within the past 2 years; 6. Severe arm pain, shoulder or elbow modified Ashworth scale spasticity score > grade 2; 7. TMS (cranial implants, ventricular shunts, pacemakers, intrathecal pumps) contraindications; 8. Cognitive impairment or mental illness that precludes the assessment; 9. Fixed joint contractures and poor skin condition; 10. Patients who are unable to sign the informed consent form or those with other conditions that the investigator considers unsuitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer-UP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Box and Block Test;ARAT motor function assessment;Modified Nottingham Sensory Function Assessment Scale;National Institutes of Health Stroke Scale, NIHSS;Ashworth Rating;modified Barthel index;Schulte square test;Montreal Cognitive Assessment, MoCA ;mental rotation test; | — |
Countries
China
Contacts
Public ContactJia Jie
Huashan Hospital, Fudan University
Outcome results
None listed