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Siewert Classification Distribution and Clinical Features of Early Esophagogastric Junction Cancer in China: A National Multicenter Retrospective Study

Siewert Classification Distribution and Clinical Features of Early Esophagogastric Junction Cancer in China: A National Multicenter Retrospective Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124655
Enrollment
Unknown
Registered
2026-05-14
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adenocarcinoma of the esophagogastric junction

Interventions

Observation group:None

Sponsors

Zhejiang Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years; 2.Lesion located within 5 cm above or below the esophagogastric junction (EGJ); 3.Pathologically confirmed adenocarcinoma; 4.Classified as early cancer, defined as tumor invasion confined to the mucosa or submucosa; 5.Availability of endoscopic, pathological, and/or surgical data sufficient for lesion localization and Siewert classification determination; 6.Cases may originate from endoscopic resection, surgical resection, or surgical resection following endoscopic treatment;

Exclusion criteria

Exclusion criteria: 1.Non-adenocarcinoma pathological type; 2.Non-early cancer (i.e., advanced cancer); 3.Lesion located outside the 5 cm range above or below the esophagogastric junction (EGJ); 4.Severe data deficiency precluding reliable lesion localization or Siewert classification determination; 5.Prior treatment(s) that significantly compromise the assessment of the primary lesion location; 6.Duplicate cases; 7.Inability to confirm the lesion as a primary tumor;

Design outcomes

Primary

MeasureTime frame
Composition ratio of Siewert classification;

Secondary

MeasureTime frame
Patient basic information (age, gender), lifestyle habits (smoking history, drinking history);Clinical features (reflux symptoms, Hp infection status, Barrett's esophagus status, background gastric mucosa condition);Lesion characteristics (lesion size, pathological type, degree of differentiation, depth of invasion, vascular invasion);Treatment information (initial treatment method, final treatment pathway);

Countries

China

Contacts

Public ContactWang Shi

Zhejiang Cancer Hospital

wangshi@zjcc.org.cn+86 571 88122217

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026