Adolescent Idiopathic Scoliosis
Conditions
Interventions
Trial group:Spinal manipulation and massage intervention: core movement spiral chain muscle activation training
frequency 45 minutes/session, 3 times/week, lasting 6 months
personalized adjustment based on electromyographic feedback
Control group:Conventional physical therapy: core muscle strength training
Sponsors
Geriatric Hospital of Hainan Province
Eligibility
Sex/Gender
All
Age
10 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with idiopathic scoliosis (AIS), aged 10–18 years; 2. Cobb angle of 10°–40°; 3. No prior spinal surgery or biologic agent treatment.
Exclusion criteria
Exclusion criteria: 1. Congenital spinal deformities or neuromuscular disorders; 2. Severe cardiopulmonary dysfunction (NYHA Class III or higher); 3. Participation in other clinical trials within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Cobb angle;Paraspinal muscle functional symmetry index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain assessment using Visual Analog Scale (VAS);Oswestry Disability Index (ODI);Quality of life assessed by Scoliosis Research Society-22 (SRS-22) questionnaire;Peripheral blood ß-catenin mRNA level;Paraspinal muscle volume and fat infiltration rate;Biological characteristics of paraspinal muscles (stiffness and elasticity);Differential expression of microRNAs;Spinal curvature-related radiographic measurements including apex vertebral translation (AVT), coronal balance (CB), and thoracic kyphosis angle (TK);Spinal morphological parameters including Cobb angle and spinal rotation deformity;Functional behavioral outcomes;Tissue molecular markers including Wnt pathway protein expression; | — |
Countries
China
Contacts
Public ContactWang Fachao
Geriatric Hospital of Hainan Province
Outcome results
None listed