Thyroid cancer
Conditions
Interventions
Young women thyroid cancer anesthesia sensitivity observation group:None
Young male thyroid cancer anesthesia sensitivity observation group:None
Middle-aged women thyroid cancer anesthesia sensitivity observation group:None
Middle-aged male thyroid cancer anesthesia sensitivity observation group:None
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18-65 years old; 2.ASA grade I-II; 3.BMI 18-30kg/m^2; 4.The menstrual cycle regularity of young female patients ( menstrual cycle regularity is defined as continuous 23-35 days, and the cycle length fluctuation does not exceed 2 days ); 5.Patients undergoing thyroid surgery; 6.Voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: 1.The following conditions are exclusion criteria: previous history of neurological diseases (epilepsy, stroke, severe traumatic brain injury); history of severe mental illness (such as schizophrenia); long-term use of psychoactive drugs or sedatives; history of drug abuse; severe liver and kidney dysfunction (Child-Pugh C, eGFR < 30 ml/min); sex hormone or related drug treatment within 6 weeks; thyroid dysfunction; history of hypothalamic or pituitary disease; allergy to sevoflurane; inability to cooperate with EEG monitoring; pregnancy or lactation; and hearing impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The end - tidal concentration of sevoflurane; | — |
Secondary
| Measure | Time frame |
|---|---|
| Prefrontal lobe EEG data;Vital signs data;Awakening period score;Quality of recovery; | — |
Countries
China
Contacts
Public ContactXuemei Sun
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed