ICU-AW
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old and = 72 hours; 6. Patients or their legal representatives provided written informed consent.
Exclusion criteria
Exclusion criteria: 1. Prior to ICU admission, patients had diseases that clearly caused muscle weakness (such as myasthenia gravis, spinal cord injury, severe hemiplegia after stroke, etc.). 2. Previous history of thyroid disease (hyperthyroidism, hypothyroidism, thyroiditis, etc.) or recent use (within 6 months) of drugs that affect thyroid function (such as amiodarone, lithium, etc.); 3. Severe trauma, burns, or amputation that prevents a limb from being assessed for muscle strength; 4. Long term bedridden (>2 weeks) or with limb dysfunction before admission; 5. Patients who underwent major surgery (especially cardiothoracic surgery, neurosurgery, orthopedic surgery) during or within 4 weeks before admission, which may significantly affect muscle strength assessment or inflammatory response; 6. Pregnant or lactating women; 7. Clinicians judged survival to be less than 24 hours or terminal.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Medical Research Council Scale;Bicarbonate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Thyroid function; | — |
Countries
China
Contacts
Dazhou Central Hospital