None
Conditions
Interventions
Intervention group:After induction of general anesthesia and before skin incision, 0.375% ropivacaine 20 mL was injected into bilateral transversus abdominis muscle under ultrasound guidance (40 mL in
Control group:The same ultrasound localization and needling steps were used, but no drug was injected or only =1 mL saline was injected.
Sponsors
The Second Hospital of Lanzhou University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=65 years 2.ASA physical status I–III 3.Undergoing elective radical gastrectomy under general anesthesia 4.Able to provide informed consent 5.Expected postoperative PCIA use
Exclusion criteria
Exclusion criteria: 1.Coagulopathy or anticoagulant use contraindicating TAPB 2.Infection at puncture site 3.Allergy to local anesthetics or sufentanil 4.Severe hepatic or renal dysfunction 5.Preexisting chronic pain or long-term opioid use 6.Cognitive impairment precluding CAM/CAM-ICU assessment 7.BMI >35 kg/m^2 (poor ultrasound visualization) 8.Conversion to open–thoracoabdominal approach intraoperatively 9.Participation in another interventional trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the curve (AUC) of resting visual analogue scale (Vas) at 48 hours after surgery;Area under the curve (AUC) of active state visual analogue scale (Vas) at 48 hours after surgery; | — |
Countries
China
Contacts
Public ContactZhijie Ma
The Second Hospital of Lanzhou University
Outcome results
None listed