Nasopharyngeal carcinoma (NPC) is a malignant tumor arising from the epithelial cells of the nasopharyngeal mucosa in the head and neck region. It occurs predominantly in the roof and lateral walls of the nasopharyngeal cavity, with a strong predilection for the pharyngeal recess (fossa of Rosenmüller). Its common clinical manifestations include blood-stained secretions upon postnasal aspiration,
Conditions
Interventions
Radiosensitive Group of Nasopharyngeal Carcinoma:None
Radioresistant Group of Nasopharyneal Carcinoma:None
Sponsors
First Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with nasopharyngeal carcinoma (NPC) confirmed by nasopharyngoscopic biopsy, with pathological types including keratinizing squamous cell carcinoma, differentiated non-keratinizing carcinoma, and undifferentiated non-keratinizing carcinoma; 2. Newly diagnosed NPC with no prior history of radiotherapy or chemotherapy; 3. Aged 18 to 70 years old, with complete medical records and no distant metastasis; 4. No history of other malignant tumors, and no concurrent other malignant tumors.
Exclusion criteria
Exclusion criteria: 1. Patients with alcohol or drug dependence; 2. Pregnant or lactating women; 3. Patients who cannot complete scheduled follow-up or are expected to be lost to follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HNRNPA2B1, ELF1, VEGFC, c-kit;VEGFC, CD34 ;HNRNPA2B1, ELF1, VEGFC, c-kit, FceRI; | — |
Countries
China
Contacts
Public ContactWang Feng
First Affiliated Hospital of Kunming Medical University
Outcome results
None listed