allergic rhinitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.AR group:Typical clinical manifestations of allergic rhinitis;Positive results for allergen-specific IgE detected by skin prick test and/or serum assay;Age between 14 and 65 years; 2.Control group:No typical clinical symptoms of AR; Negative results for skin prick test and/or serum-specific IgE test; Age between 14 and 65 years;
Exclusion criteria
Exclusion criteria: 1. Patients who have used systemic or topical corticosteroids and antibiotics within the past month, or monoclonal antibodies within the past four months; 2. Patients with nasal polyps, sinusitis, bacterial rhinitis, nasal septum deviation, atrophic rhinitis, nasal fibrosis, coagulation disorders, eosinophilic granulomatosis with polyangiitis (EGPA), acute upper respiratory tract infection, autoimmune diseases, Parkinson’s disease, or Alzheimer’s disease; 3. Pregnant woman.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| olfactory function;Pet exposure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cytokines in nasal secretions;Total IgE and allergen; | — |
Countries
China
Contacts
The Third Affiliated Hospital Sun Yat-sen University