Malignant tumors of the head and neck
Conditions
Interventions
Experimental group:Aerosol inhalation of anticholinergic drugs
Control group:Inhalation of common atomized drugs
Sponsors
Stomatological Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years old; 2.Patients undergoing resection of oral malignant tumors and cervical lymph node dissection; 3.ASA physical status I–III; 4.The patients and their family members have been fully informed of the study details, have voluntarily agreed to participate in the study, and have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients who are unable to cooperate with nebulized inhalation therapy; 2.Patients with moderate to severe symptomatic benign prostatic hyperplasia or narrow-angle glaucoma; 3.Patients with a history of myocardial infarction, severe cardiac insufficiency (New York Heart Association classification > 3), or tachyarrhythmia within the past 3 months; 4.Patients with severe respiratory tract infection accompanied by scanty and viscous sputum; 5.Patients with severe renal insufficiency who require renal replacement therapy; 6.Patients with severe hepatic insufficiency (Child-Pugh Class C); 7.Patients who have used anticholinergic drugs one day before surgery; 8.atients who refuse to participate in the trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Regional pulmonary ventilation;Sputum suction frequency;Sputum viscosity; | — |
Countries
China
Contacts
Public ContactJinrong Liao
Stomatological Hospital of Chongqing Medical University
Outcome results
None listed