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Investigation into the regulatory mechanism of TP53 on the infiltration of CD4+ and CD8+ T cells in the immune microenvironment of gastric cancer

Investigation into the regulatory mechanism of TP53 on the infiltration of CD4+ and CD8+ T cells in the immune microenvironment of gastric cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124564
Enrollment
Unknown
Registered
2026-05-13
Start date
2024-01-16
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Observational group:None

Sponsors

Huai He Hospital of Henan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients undergoing radical gastrectomy;

Exclusion criteria

Exclusion criteria: 1.Neoadjuvant radiotherapy and chemotherapy; 2.Emergency operation perforation; 3.Incomplete case data;

Design outcomes

Primary

MeasureTime frame
TP53, CD4+, and CD8+ expression levels; RNA sequencing parameters;

Secondary

MeasureTime frame
IL-2, IL-6, TNF-a, and IFN-? expression levels;

Countries

China

Contacts

Public ContactYao Kunhou

Huai He Hospital of Henan University

yaokunhou@126.com+86 13837811270

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026