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The role and mechanism of inflammatory response mediated by "tRF- 2023-XIAP-NLRP3" axis in systemic juvenile idiopathic arthritis

The role and mechanism of inflammatory response mediated by "tRF- 2023-XIAP-NLRP3" axis in systemic juvenile idiopathic arthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124562
Enrollment
Unknown
Registered
2026-05-13
Start date
2024-12-01
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Systemic juvenile idiopathic arthritis

Interventions

Observational group:None

Sponsors

The Second Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The child was diagnosed with systemic juvenile idiopathic arthritis (sJIA) in accordance with the "Chinese Expert Consensus on the Diagnosis and Treatment of Systemic Juvenile Idiopathic Arthritis (2019 Edition)" and the Pediatric Rheumatology International Trials Organization (PRINTO) classification criteria for sJIA (2018).

Exclusion criteria

Exclusion criteria: 1.Suffering from primary or secondary immunodeficiency; 2.Those with active infections including active tuberculosis, active hepatitis virus infection, bacterial infection, etc.

Design outcomes

Primary

MeasureTime frame
TRF-2023;XIAP;NLRP3;Interleukin-1ß and Interleukin-18;—

Countries

China

Contacts

Public ContactZheng Wenjie

The Second Affiliated Hospital of Wenzhou Medical University

wzwjzheng@sina.com+86 577 86689978

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026