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Cross-sectional analysis of adverse reactions of Azvudine in patients with renal impairment and network pharmacology exploration of its mechanism

Cross-sectional analysis of adverse reactions of Azvudine in patients with renal impairment and network pharmacology exploration of its mechanism

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124558
Enrollment
Unknown
Registered
2026-05-13
Start date
2025-01-01
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

SARS-COV-2

Interventions

Observation group:None

Sponsors

Zhuhai People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >=18 years, no gender restriction; 2. Continuous use of Azvudine for >=2 days, or discontinuation due to adverse drug reactions after 1 day of use; 3. No restriction on the severity of kidney injury; 4. Routine blood tests and liver and kidney function tests before and after administration.

Exclusion criteria

Exclusion criteria: 1. Patients with malignant tumors; 2. Patients in the acute phase of neurological diseases; 3. Patients with decompensated liver cirrhosis; 4. Pregnant or breastfeeding patients;

Design outcomes

Primary

MeasureTime frame
Review and analyze the incidence of adverse reactions in patients after medication (including changes in liver and kidney function, myocardial enzyme indicators, blood routine, electrolytes, etc.; gastrointestinal adverse reactions, drug allergies, etc.);

Countries

China

Contacts

Public ContactJiajian Qian

Zhuhai People's Hospital

378607273@qq.com+86 756 263 1239

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026