predominantly cystic thyroid nodules, PCTN
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosis of predominantly cystic thyroid nodules (Thyroid Imaging Reporting and Data System [TIRADS] category 2 or 3) confirmed by ultrasound, with cystic components accounting for 50% to 90%; 2. Maximum nodule diameter >= 2 cm, accompanied by cervical compression symptoms (such as dysphagia, dyspnea) or cosmetic needs; 3. Normal coagulation function (indicators such as prothrombin time and activated partial thromboplastin time within the normal reference range); 4. No history of neck surgery; 5. Refusal of surgical resection or inability to tolerate surgery due to physical conditions.
Exclusion criteria
Exclusion criteria: 1. Pure cystic nodules (cystic components > 90%), nodules with solid components > 10%, or nodules suggestive of suspected malignancy on ultrasound (TIRADS category 4 or above); 2. Complicated with hyperthyroidism or hypothyroidism that was not effectively controlled; 3. Nodules located too deeply (e.g., behind the sternum, protruding into the mediastinum), leading to a significantly increased risk of ablation; 4. Recent use of anticoagulant drugs (such as warfarin, rivaroxaban, etc.) without discontinuing the drugs as required, presence of severe coagulation disorders, or inability to cooperate with the operation; 5. Loss to follow-up or incomplete clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Complication Rate;Treatment Success Rate;Nodule Volume Reduction Ratio (VRR); | — |
Secondary
| Measure | Time frame |
|---|---|
| Cosmetic Score;Visual Analogue Scale (VAS) Score for Compressive Symptoms; | — |
Countries
China
Contacts
The Affiliated Provincial Hospital of Fuzhou University