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Study on Brain Networks and Inter-nuclei Compensatory Mechanisms in Schizophrenia Based on Deep Nuclei Regulation

Study on Brain Networks and Inter-nuclei Compensatory Mechanisms in Schizophrenia Based on Deep Nuclei Regulation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600124550
Enrollment
Unknown
Registered
2026-05-13
Start date
2026-05-15
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia

Interventions

Healthy group:None
Active group:Time-Phase Coherent Transcranial Electrical Stimulation (TI)
Sham group:Time-Phase Coherent Transcranial Electrical Stimulation (TI)

Sponsors

Hefei Fourth Peoples Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria for schizophrenia subjects: (1) Patients diagnosed with schizophrenia according to the DSM-V or ICD-10 manuals; (2) Age 18-60 years, any gender; (3) Non-acute phase, without obvious suicidal behavior or tendencies; (4) Normal vision, color perception, and hearing, right-handed. 2. Inclusion criteria for healthy subjects: (1) Age 18-60 years, any gender; (2) Normal vision, color perception, and hearing, right-handed.

Exclusion criteria

Exclusion criteria: 1. Individuals with contraindications for tES, MRI, or EEG tests, such as metal implants in the head, claustrophobia, etc.; 2. Pregnant women, those with a positive pregnancy test, or breastfeeding women; 3. Individuals with severe or uncontrollable systemic diseases (such as respiratory, circulatory, digestive, neurological, hematological, genitourinary, or endocrine system diseases); 4. Individuals who cannot sign the informed consent form or are illiterate, unwilling to comply with, or unable to complete all experimental procedures.

Design outcomes

Primary

MeasureTime frame
Function connectivity;

Secondary

MeasureTime frame
Social support level;Positive and Negative Symptom Scale (PANSS);Anxious;Coping strategies;Life events impact;Depression;

Countries

China

Contacts

Public ContactLi Wan

Hefei Fourth Peoples Hospital

wanli@ahmu.edu.cn+86 551 6361 6273

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026