Thyroid Disease
Conditions
Interventions
Opioid-Based Anesthesia + Cervical Plexus Block Group (OBA+BCSPB Group) Opioid-Sparing Anesthesia + Cervical Plexus Block Group (OSA+BCSPB Group):Remifentanil hydrochloride 0.3µg·kg-1·min-1 and cycl
Opioid-Based Anesthesia Group (OBA Group) Opioid-Sparing Anesthesia Group (OSA Group):Remifentanil hydrochloride 0.3µg·kg-1·min-1 and cyclopropofol injection 0.4-1.2 mg·kg-1·h-1 were continuously inf
Less opioid anesthesia + cervical plexus block group (OSA+BCSPB group):Esketamine 0.12mg·kg·h and cyclopropofol 0.4-1.2 mg·kg-1·h-1 were continuously infused until the end of surgery. Dexmedetomidine
Reduced opioid anesthesia group (OSA group):Esketamine 0.12mg·kg·h and cyclopropofol 0.4-1.2 mg·kg-1·h-1 were continuously infused until the end of surgery. Dexmedetomidine injection 0.5-1 µg·kg·h was
Sponsors
General Hospital of Ningxia Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients aged 18 to 70 years, classified as ASA I-III, undergoing elective thyroid surgery.
Exclusion criteria
Exclusion criteria: Patients with a history of neck surgery, a history of infection at the surgical site, hypothyroidism, hyperthyroidism, substernal goiter, large cervical thyroid tumor, chronic pain requiring opioid therapy before or after surgery, excessive alcohol consumption, electrolyte disturbances, pregnancy, coagulation disorders, other surgical interventions, allergic reactions or contraindications to the drugs used in this study, as well as patients who do not agree to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of nausea and vomiting in the first 24 hours after surgery;Quality was restored 24 hours after surgery;Postoperative pain and remedial times; | — |
Countries
China
Contacts
Public ContactXuexin Chen
General Hospital of Ningxia Medical University
Outcome results
None listed