Stroke
Conditions
Interventions
Ipsilateral ankle loading treadmill training group:Treadmill training with ipsilateral ankle loading at 2% of body weight, 30 minutes per session, 3 sessions per week for 4 weeks. The initial treadmil
Ipsilateral ankle combined with contralateral waist loading treadmill training group:Treadmill training with ipsilateral ankle loading at 1% of body weight combined with contralateral waist loading at
Unloaded treadmill training control group:Treadmill training without loading, 30 minutes per session, 3 sessions per week for 4 weeks. The initial treadmill speed will be set to the participant's comf
Sponsors
Shaanxi Provincial Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 40 and 65 years, diagnosed with stroke according to the diagnostic criteria established by the National Cerebrovascular Disease Conference of China, and confirmed by computed tomography or magnetic resonance imaging; 2. First-ever stroke, with disease duration between 3 months and 2 years; 3. Unilateral limb hemiplegia; 4. Holden Functional Ambulation Category >= grade 2, able to walk independently for at least 10 meters without physical assistance; 5. Mini-Mental State Examination score >= 24, able to understand and follow instructions; 6. Able to walk continuously on a treadmill for at least 5 minutes; 7. Willing to participate and provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Presence of other neurological or musculoskeletal disorders that severely affect walking function; 2. Presence of severe cardiac, pulmonary, hepatic, renal, or other organ dysfunction; 3. Severe spasticity of the affected lower limb (modified Ashworth scale > grade 2) or limited range of motion; 4. Presence of severe visual impairment or vestibular dysfunction affecting balance; 5. Participation in other clinical trials that may affect walking function; 6. Presence of contraindications to treadmill training (e.g., unstable angina, uncontrolled hypertension, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Step length asymmetry ratio;Single support time asymmetry ratio;Range of motion asymmetry ratio of the hip, knee, and ankle joints in the sagittal plane;Peak joint moment asymmetry ratio of the hip, knee, and ankle joints; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment for Lower Extremity;Six-minute walk test distance;Borg Rating of Perceived Exertion (6-20 scale);Incidence of adverse events; | — |
Countries
China
Contacts
Public ContactChen Longwei
Shaanxi Provincial Rehabilitation Hospital
Outcome results
None listed