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A Retrospective study research of anlotinib combined with Anti-PD-1 inhibitors in Treating advanced solid tumors

A Retrospective study research of anlotinib combined with Anti-PD-1 inhibitors in Treating advanced solid tumors

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124529
Enrollment
Unknown
Registered
2026-05-13
Start date
2023-05-01
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer (NSCLC)

Interventions

Observation group:None

Sponsors

The Second Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with advanced solid tumors confirmed by histology; 2. Age 14 years; 3. Presence of at least one measurable target lesion to demonstrate drug response according to the Response Evaluation Criteria in Solid Tumors (RECIST 1.1); 4. Patients receiving combined treatment with anlotinib and anti-PD-1 inhibitors; 5. Eastern Cooperative Oncology Group performance status (ECOG PS) of <=2.

Exclusion criteria

Exclusion criteria: 1. Previous use of Anlotinib; 2. Patients with clinically active brain metastases; 3. Patients with active autoimmune diseases or a history of autoimmune diseases; 4. Accompanied by another serious disease that may threaten the patient's survival, such as severe cerebrovascular disease, acute myocardial infarction, and advanced liver cirrhosis; 5. Efficacy evaluation data not available;

Design outcomes

Primary

MeasureTime frame
progression free survival;

Secondary

MeasureTime frame
progression free survival;

Countries

China

Contacts

Public ContactDan Lu

The Second Affiliated Hospital of Harbin Medical University

doctorlu1972@163.com+86 451 86605264

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026