Rotator Cuff Injury
Conditions
Interventions
Observation group: Low-intensity focused ultrasound combined with Jintiange capsules:None
Control group: Low-intensity focused ultrasound alone:None
Sponsors
First Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily participate in this study and sign informed consent. 2. Aged 18-75 years, male or female; 3. Shoulder pain lasting for at least 4 weeks, with VAS score >= 5; 4. No participation in any drug or medical device trials within 3 months prior to enrollment. 5. Clinically diagnosed with chronic shoulder pain, confirmed as partial-thickness rotator cuff tear or chronic tendinopathy by MRI or ultrasound (excluding acute full-thickness tears requiring surgical intervention).
Exclusion criteria
Exclusion criteria: 1. Patients in poor general condition who are unable to objectively describe symptoms or cooperate with questionnaire assessments; 2. Patients with imaging or surgically confirmed complete rotator cuff tear requiring direct surgical repair; 3. Patients with concomitant shoulder dislocation, acute fracture, infection, malignant tumor, or other conditions that may affect efficacy assessment; 4. Patients with a history of prior shoulder surgery, or severe soft tissue adhesion and mobility impairment; 5. Patients with malignant tumor or severe organic disease, as well as those with severe cardiac, hepatic, or renal insufficiency, or psychiatric disorders affecting compliance; 6. Patients with coagulation dysfunction or those receiving anticoagulant therapy; 7. Patients with ulceration, redness, swelling, or active inflammatory infection of the affected shoulder joint; or those with systemic severe infection or inflammation; or patients with neurological or psychiatric disorders; 8. Pregnant or breastfeeding women. 9. Contraindications or allergy to the study drug (Jintiange capsules) or treatment device (focused ultrasound); 10. Patients who have participated in other interventional clinical trials and have not completed at least a 4-week washout period; 11. Patients judged by the research team to be unsuitable for enrollment, such as those lacking compliance ability or with difficulty in follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain assessment: Visual Analogue Scale (VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of shoulder joint function;IL-6; | — |
Countries
China
Contacts
Public ContactZhang Xiaolina
First Affiliated Hospital of Kunming Medical University
Outcome results
None listed