Head and neck squamous cell carcinoma (Stage III or IV)
Conditions
Interventions
Total Laryngectomy Group:None
Partial Laryngectomy Group:None
Sponsors
The first affiliated hostipal of nanchang university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Diagnosed with head and neck squamous cell carcinoma at the First Affiliated Hospital of Nanchang University from January 2014 to January 2024, with primary sites including the larynx (supraglottic type/glottic type/subglottic type), hypopharynx, oropharynx, etc. 2.Histologically confirmed squamous cell carcinoma. 3.Clinical stage III, IVA, or IVB (according to the AJCC/UICC 8th edition staging system), with no distant metastasis (M0). 4.Underwent surgical treatment as the initial radical treatment, with concurrent neck dissection performed during the operation. 5.Had complete baseline clinical, pathological, and staging data. 6.Post-treatment follow-up duration = 6 months (unless an event occurred within 6 months).
Exclusion criteria
Exclusion criteria: 1.Presence of distant metastasis (M1). 2.Received non-surgical treatment (such as radiotherapy alone/chemoradiotherapy) as the initial treatment. 3.Received neoadjuvant chemotherapy or radiotherapy before surgery. 4.Had a second primary carcinoma in the head and neck region. 5.Medical records were severely incomplete, making accurate staging or efficacy evaluation impossible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 5-year overall survival rate;5-year disease-specific survival rate;5-year disease-free survival rate; | — |
Countries
China
Contacts
Public ContactYanan Liu
The first affiliated hostipal of nanchang university
Outcome results
None listed