Recovery of gastrointestinal function after colorectal surgery
Conditions
Interventions
Group S:Intravenous administration of sufentanil at a dose of 0.3–0.5 µg/kg
Group T:Intravenous administration of tegileridine at a dose of 15–25 µg/kg
Sponsors
The First People’s Hospital of Lianyungang
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-65 years; 2. BMI 18~30kg/m^2; 3. ASAI~III; 4. Patients who are scheduled to undergo elective colorectal surgery and have not undergone an enterostomy; 5. Have a clear understanding and voluntarily participate in this study, and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1. Individuals with a history of opioid allergy or allergies to experimental drugs; 2. Combine patients with severe cardiovascular and cerebrovascular diseases, lung diseases, respiratory dysfunction, and liver and kidney dysfunction; 3. Patients with mental illness or a history of mental illness; 4. Long term use of painkillers, psychotropic drugs, hormones, or nonsteroidal anti-inflammatory drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| I-FEED score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Resting Pain VAS Score;Effective pressing frequency of analgesic pump;QoR-15 score;Pulmonary complication assessment;Sleep Quality Score;The level of intestinal type fatty acid binding protein (I-FABP) in the patient's venous blood; | — |
Countries
China
Contacts
Public ContactWu Yong
The First People’s Hospital of Lianyungang
Outcome results
None listed