Patients with impaired cardiac sympathetic activity
Conditions
Interventions
18F-MFBG PET / CT imaging group:None
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 95 Years
Inclusion criteria
Inclusion criteria: 1. The study participants voluntarily or legal guardians agree to participate in this trial and sign an informed consent form; 2. Age >=18 years and <=95 years (the date of signing the informed consent form) is not limited to gender; 3. Meet the diagnostic criteria for cardiovascular diseases such as hypertension, coronary artery disease, heart failure, and arrhythmia, or other patients such as PD and DLB that can cause impaired cardiac sympathetic nerve activity; 4. Expected survival time to exceed 12 months; 5. Willing and able to comply with diagnostic plans, clinical laboratory tests and other trial procedures.
Exclusion criteria
Exclusion criteria: 1. Known to allergies to injections or their auxiliary agents; 2. Can't lie flat or stay still while performing a PET scan, or be intolerant of a PET scan; 3. Study participants had abnormalities in physical examinations, ECG and clinical laboratory examinations during the screening period, which, as determined by the investigator, may affect safety or compliance; 4. The researchers believe that it is not suitable to participate in this experiment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ratio of heart to mediastinum (H/M);sensitivity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Elution rate (WR); | — |
Countries
China
Contacts
Public ContactYang Hongjie
Peking University Shenzhen Hospital
Outcome results
None listed