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Assessment of disease activity in Takayasu arteritis by Ultra-Resolution Microscopy Imaging

A prospective cohort study on the association between skin barrier function in the elderly and systemic chronic diseases, and the impact of skin care interventions

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124461
Enrollment
Unknown
Registered
2026-05-12
Start date
2026-05-14
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Takayasu arteritis

Interventions

Clinically active group:NA
Clinically inactive group:NA

Sponsors

The First Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patient meets the 2022 American College of Rheumatology classification criteria for large artery vasculitis. Specific criteria are as follows: (The patient can be diagnosed with large artery vasculitis if the necessary conditions are met and the total classification score is >=5 points.) Necessary condition: Age at onset = 20 mmHg between both upper limbs, 1 point. (2) Other imaging criteria: 1) Number of affected arteries: 1, 2, or >=3 (choose one), scoring 1, 2, or 3 points respectively; 2) Symmetric involvement of paired arteries, 1 point; 3) Involvement of the abdominal aorta with renal or mesenteric involvement, 3 points.

Exclusion criteria

Exclusion criteria: 1. TA does not involve the carotid arteries. 2. Contraindications to contrast-enhanced ultrasound, such as allergy to ultrasound contrast agents. 3. Failure to establish peripheral venous access. 4. Suboptimal image quality on CEUS, making data analysis unfeasible.

Design outcomes

Primary

MeasureTime frame
CEUS enhancement grade;URM Density;URM Location Velocity;Perfusion Index;

Countries

China

Contacts

Public ContactYang Bai

The First Hospital of China Medical University

baiyangfriend1984@163.com+86 139 4048 2262

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026