forehead wrinkle
Conditions
Interventions
control group:NA
Intervention group:Application of lidocaine cream externally
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.18 to 65 years old (inclusive of both upper and lower limits), open to both men and women; 2.When raising the eyebrows, there are clearly visible wrinkles on the forehead: the FWS (Facial Wrinkle Score Scale) score is >=1 point. 3.Understand the treatment of botulinum toxin and voluntarily participate in this trial;
Exclusion criteria
Exclusion criteria: 1.Having received botulinum toxin treatment within the past six months; 2.Previous treatment with botulinum toxin was ineffective or resulted in an allergic reaction; 3.Penicillin allergy; 4.Have severe chronic diseases and are currently taking medications that are contraindicated when using botulinum toxin, such as muscle relaxants or commonly used antibiotics. 5.Patients with myasthenia gravis and ptosis of the upper eyelid; 6.Pregnant and lactating women; 7.Currently participating in other clinical trials, or having been involved in clinical trials that affect this study for less than 3 months. 8.Previously undergone forehead wrinkle removal surgery with impaired frontal muscle movement, or damage to the frontal branch of the facial nerve resulting in inability to raise the eyebrows normally; 9.Unable to cooperate with regular follow-ups; 10.Other situations judged by the researchers as not meeting the inclusion criteria;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of botulinum toxin treatment on both sides;Changes in perspiration;Changes in skin pores; | — |
Countries
China
Contacts
Public Contactxie yun
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed